With Spurs trailing 1-0 in the second half at St Mary’s, Kane appeared to hurt his left hamstring in the process of scoring a goal that was ruled out for offside.
The England captain was duly taken off, with Erik Lamela taking his place, and Tottenham will now await news on the severity of their talisman’s injury.
Prior to Wednesday’s clash with Southampton, Kane had missed just five minutes of Premier League action this season.
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